Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197659 | 0.87 | LMNA (0.59) | LMNAGAAKMT2AALDH1A1NPC1 | |
| SCHEMBL6195867 | 0.84 | LMNA (0.53) | LMNAGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL6196494 | 0.84 | LMNA (0.60) | LMNAGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL6197598 | 0.84 | LMNA (0.53) | LMNAGAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6196338 | 0.84 | LMNA (0.53) | LMNAGAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6198576 | 0.81 | LMNA (0.53) | LMNAGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL6198044 | 0.81 | LMNA (0.50) | LMNAGAAMAPTHPGDMAOB | |
| SCHEMBL6195803 | 0.80 | LMNA (0.49) | LMNAGAAKMT2AMAPTRAB9A | |
| SCHEMBL6195402 | 0.80 | LMNA (0.51) | LMNAGAAKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6200128 | 0.76 | LMNA (0.50) | LMNAGAAKMT2ATDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |