Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15926545 | 0.79 | LMNA (0.48) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL14817553 | 0.72 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL8849930 | 0.71 | MEN1 (0.50) | LMNACYP2C9 | |
| SCHEMBL12593645 | 0.70 | — | — | |
| SCHEMBL173113 | 0.69 | CHRM2 (0.61) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7793301 | 0.67 | KDM1A (0.31) | — | |
| SCHEMBL372614 | 0.63 | CYP2C9 (0.55) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL21548014 | 0.63 | CYP2C9 (0.55) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL22113161 | 0.63 | CYP2C9 (0.55) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL1573636 | 0.63 | CYP2C9 (0.55) | CHRM2CHRM4CHRM1CHRM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658925-A | EXHIBITS SEROTONIN ANTAGONISM AND AN ACETYLCHOLINE RELEASE ACCELERATING ACTIVITY | EISAI CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0645391-A2 | Aminobenzoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-03-29 | — | — | EP | disclosed |