Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13397682 | 1.00 | THRB (0.61) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL27686916 | 0.98 | THRB (0.59) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL27530190 | 0.98 | THRB (0.59) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL159921 | 0.98 | THRB (0.59) | THRBTSHRCYP4F2CYP4A11HTT | |
| 1,4-Butanediol SCHEMBL16265704 | 0.96 | THRB (0.66) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL6115523 | 0.94 | TSHR (0.61) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL4933888 | 0.94 | TSHR (0.61) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL5909577 | 0.94 | TSHR (0.61) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL8037801 | 0.94 | TSHR (0.61) | THRBTSHRCYP4F2CYP4A11HTT | |
| SCHEMBL6114698 | 0.94 | TSHR (0.61) | THRBTSHRCYP4F2CYP4A11HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661307-B1 | Transparent resin and plastic lens | HITACHI CHEMICAL CO LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5663264-A | OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5583191-A | FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0661307-A2 | Transparent resin and plastic lens | HITACHI CHEMICAL CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |