Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513604 | 0.78 | TRPV1 (0.83) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL7751798 | 0.76 | MAPT (0.49) | MAPT | |
| SCHEMBL4689121 | 0.76 | MEN1 (0.46) | MAPTEPHX2 | |
| SCHEMBL8363736 | 0.74 | NPC1 (0.76) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL15948139 | 0.74 | TRPV1 (0.76) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL3238671 | 0.74 | CA1 (0.53) | NPC1RAB9AMAPT | |
| SCHEMBL9499536 | 0.73 | TRPV1 (0.57) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL674439 | 0.73 | HDAC6 (0.82) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL2064051 | 0.73 | TRPV1 (0.73) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL11730950 | 0.73 | NPC1 (0.77) | TRPV1PTGS1NPC1RAB9ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618801-A | ADMINISTERING SUBSTITUTED DIALKOXYPHOSPHINOYLMETHYLBENZAMIDE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-04-08 | — | — | US | disclosed |