Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.66 |
| ▸ | TDO2 | P48775 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008631 | 0.86 | IDO1 (0.50) | IDO1TDO2ALDH1A1L3MBTL1SLC6A2 | |
| SCHEMBL73865 | 0.84 | IDO1 (0.70) | IDO1TDO2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL11076842 | 0.84 | IDO1 (0.47) | IDO1TDO2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL9934266 | 0.82 | IDO1 (0.46) | IDO1TDO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1773224 | 0.82 | SLC6A4 (0.54) | IDO1TDO2ALDH1A1L3MBTL1SLC6A2 | |
| SCHEMBL461448 | 0.81 | IDO1 (0.47) | IDO1TDO2SLC6A2SLC6A4CHRM2 | |
| SCHEMBL8851108 | 0.80 | IDO1 (0.60) | IDO1TDO2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL23296602 | 0.79 | IDO1 (0.46) | IDO1TDO2SLC6A2SLC6A4CHRM2 | |
| SCHEMBL30608097 | 0.78 | IDO1 (0.47) | IDO1TDO2ALDH1A1L3MBTL1SLC6A2 | |
| SCHEMBL511201 | 0.78 | IDO1 (0.47) | IDO1TDO2ALDH1A1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529444-B1 | 2-Arylpropenic acids and their utilisation in the preparation of 5-ketoprofen | BAYER AG (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5362907-A | Intermediates and their use in the preparation of s-ketoprofen | BAYER AKTIENGESELLSCHAFT (DE) | 1994-11-08 | — | — | US | disclosed |
| EP-0529444-A2 | 2-Arylpropenic acids and their utilisation in the preparation of 5-ketoprofen | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |