SCHEMBL73865

SCHEMBL73865

Brc1cccc(C(OC(c2ccccc2)c2cccc(Br)c2)c2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.70
TDO2 P48775 5/20 0.70
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAOB P27338 1/20 0.39
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD1 P21728 1/20 0.38
TBXA2R P21731 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
IDO2 Q6ZQW0 1/20 0.37
MAPK1 P28482 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8850690 0.84 IDO1 (0.66) IDO1TDO2ALDH1A1TDP1MAOB
SCHEMBL3597509 0.80 HTR2A (0.54) IDO1TDO2ALDH1A1TDP1CHRM2
SCHEMBL8851108 0.80 IDO1 (0.60) IDO1TDO2ALDH1A1MAOBCHRM2
SCHEMBL127629 0.79 IDO1 (0.46) IDO1TDO2CHRM2ADRA2ACHRM1
SCHEMBL28548488 0.78 IDO1 (0.58) IDO1TDO2CHRM2HTR1AADRA2A
Ammonia Solution, Strong SCHEMBL7282272 0.77 IDO1 (0.44) IDO1TDO2CHRM2ADRA2ACHRM1
Water SCHEMBL11878861 0.77 IDO1 (0.44) IDO1TDO2CHRM2ADRA2ACHRM1
Methane SCHEMBL29089947 0.77 IDO1 (0.44) IDO1TDO2CHRM2ADRA2ACHRM1
SCHEMBL6171510 0.76 IDO1 (0.48) IDO1TDO2ALDH1A1
SCHEMBL4426836 0.76 IDO1 (0.55) IDO1TDO2ALDH1A1TDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8792318-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-29 US disclosed
US-8369204-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-05 US disclosed
US-8289833-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-10-16 US disclosed
US-20120155242-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-06-21 US disclosed
US-8129496-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-06 US disclosed
US-20120033539-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-02-09 US disclosed
US-20120034383-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-02-09 US disclosed
US-8102753-B2 Method for forming deformed regions in a resin layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-01-24 US disclosed
EP-1994078-B1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING IBM (US) 2009-07-01 EP disclosed
EP-1994078-A2 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING International Business Machines Corporation (US) 2008-11-26 EP disclosed
US-20080219135-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING GLOBALFOUNDRIES U.S. INC. 2008-09-11 US disclosed
WO-2007096359-A2 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-08-30 WO disclosed
US-20070195682-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING GLOBALFOUNDRIES INC. (KY) 2007-08-23 US disclosed
US-20070196645-A1 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-08-23 US disclosed