Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.74 |
| ▸ | RARG | P13631 | 13/20 | 0.74 |
| ▸ | RARA | P10276 | 6/20 | 0.74 |
| ▸ | RARB | P10826 | 6/20 | 0.74 |
| ▸ | RXRB | P28702 | 3/20 | 0.74 |
| ▸ | RXRG | P48443 | 3/20 | 0.74 |
| ▸ | PPARG | P37231 | 10/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850686 | 1.00 | RXRA (0.74) | RXRARARGRARARARBRXRB | |
| SCHEMBL8850533 | 1.00 | RXRA (0.74) | RXRARARGRARARARBRXRB | |
| SCHEMBL8850541 | 1.00 | RXRA (0.74) | RXRARARGRARARARBRXRB | |
| SCHEMBL8850336 | 0.85 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL6049839 | 0.85 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL6049845 | 0.85 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL6049843 | 0.85 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL8850333 | 0.85 | RXRA (1.00) | RXRARARGRARARARBRXRB | |
| SCHEMBL8145871 | 0.83 | RXRA (0.53) | RXRARARGRARARARBRXRB | |
| SCHEMBL8145874 | 0.83 | RXRA (0.53) | RXRARARGRARARARBRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800503-A1 | NOVEL TRIENOIC RETINOID COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |