Methacrylic Acid

Methacrylic Acid

SCHEMBL8850801

C=C(C)C(=O)O.C=C(C)C(=O)O.CCC(CO)(CO)C(C)C

nearest known ligand 0.36

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.32
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28135989 0.90 TGFBR1 (0.35) TGFBR1TSHRALDH1A1TDP1
Methacrylic Acid SCHEMBL8851043 0.85 TGFBR1 (0.31) TGFBR1
Methacrylic Acid SCHEMBL5999378 0.80
Methacrylic Acid SCHEMBL27853217 0.80 TGFBR1 (0.32) TGFBR1TSHRALDH1A1TDP1
SCHEMBL765917 0.80 DPP4 (0.35) TSHRALDH1A1TDP1
Methacrylic Acid SCHEMBL35549 0.78 TGFBR1 (0.37) TGFBR1TSHRALDH1A1TDP1
Methacrylic Acid SCHEMBL447936 0.78 TGFBR1 (0.37) TGFBR1TSHRALDH1A1TDP1
Methacrylic Acid SCHEMBL35273 0.78 TGFBR1 (0.37) TGFBR1TSHRALDH1A1TDP1
Methacrylic Acid SCHEMBL28229341 0.77 CHRM1 (0.34) TGFBR1TSHRTDP1
Methacrylic Acid SCHEMBL2818349 0.77 CHRM1 (0.34) TGFBR1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661307-B1 Transparent resin and plastic lens HITACHI CHEMICAL CO LTD (JP) 1997-10-15 EP disclosed
US-5663264-A OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-09-02 US disclosed
US-5583191-A FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-12-10 US disclosed
EP-0661307-A2 Transparent resin and plastic lens HITACHI CHEMICAL CO., LTD. (JP) 1995-07-05 EP disclosed