Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820877 | 0.87 | GRIN2D (0.41) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL27612149 | 0.87 | HIF1A (0.41) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL18051630 | 0.85 | CYP2C19 (0.40) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL8850502 | 0.85 | ELANE (0.41) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL28967705 | 0.83 | KCNN4 (0.41) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL8850991 | 0.83 | TSHR (0.42) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL8034194 | 0.82 | HIF1A (0.59) | HIF1ACYP2C19TDP1POLBALDH1A1 | |
| SCHEMBL8850755 | 0.81 | ALDH1A1 (0.40) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL238398 | 0.80 | ELANE (0.38) | HIF1ACYP2C19ELANETDP1POLB | |
| SCHEMBL3180129 | 0.79 | CYP2C19 (0.46) | HIF1ACYP2C19ELANETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661307-B1 | Transparent resin and plastic lens | HITACHI CHEMICAL CO LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5663264-A | OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5583191-A | FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0661307-A2 | Transparent resin and plastic lens | HITACHI CHEMICAL CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |