Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195344 | 0.84 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTSOAT1TSHR | |
| SCHEMBL8681188 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTSOAT1HTT | |
| SCHEMBL8683134 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTSOAT1HTT | |
| SCHEMBL8681288 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTSOAT1HTTPOLB | |
| SCHEMBL2143739 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTSOAT1HTT | |
| SCHEMBL2323069 | 0.75 | KMT2A (0.35) | ALDH1A1GAAMAPTSOAT1SMN1; SMN2 | |
| SCHEMBL3629079 | 0.75 | GAA (0.70) | ALDH1A1GAAMAPTHTTPOLB | |
| SCHEMBL15189723 | 0.73 | GAA (0.36) | ALDH1A1GAAMAPTSOAT1CHRM1 | |
| SCHEMBL2322368 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTSOAT1POLBL3MBTL1 | |
| SCHEMBL27725218 | 0.71 | MAPT (0.57) | ALDH1A1GAAMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679692-A | ANTIASTHMATIC, ANTIALLERGENS AND ANTIINFLAMMATORY AGENT | SCHERING CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5665735-A | ANTIASTHMATIC, ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0635012-B1 | UNBRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE | SCHERING CORP (US) | 1996-07-10 | — | — | EP | disclosed |
| EP-0635012-A1 | UNBRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE. | SCHERING CORP (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993020063-A1 | UNBRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |