Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852144 | 0.90 | SAT1 (0.31) | SAT1 | |
| SCHEMBL8851210 | 0.83 | KISS1R (0.31) | — | |
| SCHEMBL8852197 | 0.82 | CACNA2D1 (0.35) | — | |
| SCHEMBL8851181 | 0.78 | — | — | |
| SCHEMBL8852102 | 0.76 | CACNA2D1 (0.41) | CYP2C19 | |
| SCHEMBL8851755 | 0.76 | — | — | |
| SCHEMBL8851196 | 0.75 | — | — | |
| SCHEMBL8852336 | 0.75 | CACNA2D1 (0.32) | — | |
| SCHEMBL8851145 | 0.75 | HTT (0.30) | — | |
| SCHEMBL8851909 | 0.74 | SLC6A4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618814-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating multi-drug resistance and pharmaceutical compositions containing these compounds | DR. KARL THOMAE GMBH (DE) | 1997-04-08 | — | — | US | disclosed |