SCHEMBL8851529

SCHEMBL8851529

OCCCCCCCC[S]

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
MIF P14174 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GPR84 Q9NQS5 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8850614 1.00 LMNA (0.44) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL8850648 1.00 LMNA (0.44) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL8850500 1.00 LMNA (0.44) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL2050089 1.00
SCHEMBL8850669 1.00 LMNA (0.44) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL2048070 1.00
SCHEMBL8850594 1.00 LMNA (0.44) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL8850681 1.00 LMNA (0.44) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL1806116 0.96
SCHEMBL934417 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0488381-B1 Polyhydroxyphenylene ether resin and process for preparing the same MITSUBISHI CHEM CORP (JP) 1997-01-29 EP disclosed
EP-0513812-B1 Thermoplastic resin composition MITSUBISHI CHEM CORP (JP) 1996-03-27 EP disclosed
US-5202409-A POLYHYDROXYPHENYLENE ETHER RESIN AND PROCESS FOR PREPARING THE SAME MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-04-13 US disclosed
EP-0513812-A2 Thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1992-11-19 EP disclosed
EP-0488381-A1 Polyhydroxyphenylene ether resin and process for preparing the same MITSUBISHI CHEMICAL CORPORATION (JP) 1992-06-03 EP disclosed