Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 6/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852505 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8851982 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8982735 | 0.89 | MEN1 (0.69) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6212047 | 0.89 | MEN1 (0.69) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8982748 | 0.89 | MEN1 (0.68) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8982756 | 0.89 | MEN1 (0.68) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL9231698 | 0.88 | MEN1 (0.52) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL680074 | 0.87 | KCNH2 (0.69) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8982761 | 0.86 | KCNH2 (0.68) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8982774 | 0.86 | KCNH2 (0.68) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578604-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | claimed |
| EP-0671391-A1 | 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids | BAYER AG (DE) | 1995-09-13 | — | — | EP | claimed |
| JP-7285941-A | — | — | None | — | — | JP | disclosed |
| US-5659038-A | GRAMPOSITIVE/GRAMNEGATIVE MICROBIOCIDES; ANTISEPTICS, HUMAN AND VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
| US-5578604-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| JP-H07285941-A | 5-VINYL-AND 5-ETHINYL-QUINOLONE-AND-NAPHTHYRIDONE-CARBOXYLIC ACID | BAYER AG | 1995-10-31 | — | — | JP | disclosed |
| EP-0671391-A1 | 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids | BAYER AG (DE) | 1995-09-13 | — | — | EP | disclosed |