Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 1/20 | 1.00 |
| ▸ | CA12 | O43570 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | CA9 | Q16790 | 1/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 1.00 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.59 |
| ▸ | KDM4A | O75164 | 1/20 | 0.58 |
| ▸ | KDM4B | O94953 | 1/20 | 0.58 |
| ▸ | KDM5C | P41229 | 1/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.58 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 3/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinazolinone SCHEMBL30408864 | 0.98 | PARP1 (0.96) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| SCHEMBL20998623 | 0.98 | PARP1 (0.96) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL29603643 | 0.98 | PARP1 (0.96) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL8201420 | 0.98 | PARP1 (0.96) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL22442340 | 0.98 | PARP1 (0.96) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL9541428 | 0.91 | PARP1 (0.82) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL15691341 | 0.91 | PARP1 (0.82) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL29800668 | 0.89 | PARP1 (0.79) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL31483770 | 0.85 | PARP1 (0.72) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| Quinazolinone SCHEMBL30077212 | 0.84 | PARP1 (0.72) | PARP1PDPK1CA12ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5218 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4745138-A1 | THIO-GLUTARIMIDO ISOINDOLINONE DERIVATIVE, BIFUNCTIONAL PROTEIN DEGRADER CONTAINING SAME, AND USES THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | claimed |
| EP-3840748-B1 | SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT | CLAVIUS PHARMACEUTICALS LLC (US) | 2026-04-15 | — | — | EP | claimed |
| EP-4263518-B1 | NEW QUINAZOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2026-04-01 | — | — | EP | claimed |
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | claimed |
| US-20250243210-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADER DEVELOPED BASED THEREON AND THEIR APPLICATIONS | GLUETACS THERAPEUTICS (SHANGHAI) CO., LTD. (CN) | 2025-07-31 | — | — | US | claimed |
| WO-2025132758-A1 | PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-26 | — | — | WO | claimed |
| CN-120202200-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione-based compounds and applications thereof | 标新生物医药科技(上海)有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119954731-A | Chalcone derivative containing 4-quinazolinone structure, and preparation method and application thereof | 黔南州烟草公司平塘县分公司 | 2025-05-09 | — | — | CN | claimed |
| CN-116693554-B | Quinazoline-4-ketone compound containing 1,2, 4-triazole [3,4-b ] [1,3,4] thiadiazole, preparation and application | 贵州大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119640277-A | Method for electrocatalytic synthesis of quinazolinone derivatives | 宁夏医科大学 | 2025-03-18 | — | — | CN | claimed |
| EP-0098589-B1 | QUINAZOLINE DERIVATIVES WHICH ARE ACTIVE AGAINST COCCIDIOSIS | VETEM S.p.A. (IT) | 1987-12-09 | — | — | EP | claimed |
| US-4632926-A | Quinazolinone derivatives which are active against coccidiosis | VETEM S.P.A. (IT) | 1986-12-30 | — | — | US | claimed |
| EP-0056637-B1 | 4(3H)-QUINAZOLINONE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS | Ishikawa, Masayuki (JP) | 1985-07-24 | — | — | EP | claimed |
| EP-0056157-B1 | USE OF 7-HYDROXY-COUMARIN COMPOUNDS FOR IMPREGNATING PAPER | BAYER AG (DE) | 1985-05-29 | — | — | EP | claimed |
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | claimed |
| EP-0098589-A1 | Quinazoline derivatives which are active against coccidiosis | VETEM S.p.A. (IT) | 1984-01-18 | — | — | EP | claimed |
| US-4411946-A | FORGERY-PROOF PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-10-25 | — | — | US | claimed |
| EP-0003771-B1 | CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-10-20 | — | — | EP | claimed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | claimed |
| US-4113637-A | DISPERSANTS, DETERGENTS | INSTITUT FRANCAIS DU PETROLE (FR) | 1978-09-12 | — | — | US | claimed |