Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 7/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | IAPP | P10997 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324157 | 0.85 | ALDH1A1 (0.69) | BACE1ALDH1A1CYP3A4RECQLESR1 | |
| SCHEMBL9742780 | 0.84 | ALDH1A1 (0.68) | BACE1ALDH1A1CYP3A4RECQLTP53 | |
| SCHEMBL9742784 | 0.84 | ALDH1A1 (0.68) | BACE1ALDH1A1CYP3A4RECQLTP53 | |
| SCHEMBL1824386 | 0.83 | LCK (0.61) | BACE1ALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL1824384 | 0.83 | LCK (0.61) | BACE1ALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL6056802 | 0.82 | BACE1 (0.48) | BACE1ALDH1A1CYP3A4RECQLESR1 | |
| SCHEMBL6056797 | 0.82 | BACE1 (0.48) | BACE1ALDH1A1CYP3A4RECQLESR1 | |
| SCHEMBL5837450 | 0.82 | TUBB1 (0.46) | BACE1ALDH1A1CYP3A4RECQLTDP1 | |
| SCHEMBL9421133 | 0.82 | TUBB1 (0.46) | BACE1ALDH1A1CYP3A4RECQLTDP1 | |
| SCHEMBL10778611 | 0.80 | ESR1 (0.53) | BACE1ALDH1A1CYP3A4RECQLESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670589-A | COORDINATION POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-23 | — | — | US | disclosed |