Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 10/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853329 | 0.83 | GSK3B (0.68) | NOTUMNOX1GSK3BHSD17B3BCHE | |
| SCHEMBL9629768 | 0.78 | GSK3B (0.57) | NOTUMNOX1GSK3BHSD17B3BCHE | |
| SCHEMBL30198410 | 0.71 | NOX1 (1.00) | NOX1BCHEGAAMAPTPOLB | |
| SCHEMBL341905 | 0.71 | NOX1 (1.00) | NOX1BCHEGAAMAPTPOLB | |
| SCHEMBL8853311 | 0.71 | GSK3B (0.68) | NOTUMGSK3BBCHETHRBMAPT | |
| SCHEMBL19546120 | 0.69 | NOTUM (0.67) | NOTUMNOX1HSD17B3GAAMAPT | |
| SCHEMBL10352868 | 0.69 | NOTUM (0.82) | NOTUMNOX1HSD17B3GAAPOLB | |
| SCHEMBL9628923 | 0.68 | NOTUM (0.79) | NOTUMNOX1HSD17B3GAAPOLB | |
| SCHEMBL19918200 | 0.68 | THRB (0.64) | NOTUMGSK3BTHRBMAPTSMN1; SMN2 | |
| SCHEMBL19229613 | 0.67 | NOX1 (0.76) | NOX1BCHEGAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657407-B1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5475164-A | Process for preparing 3-fluoro-4,6-dichlorotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0657407-A1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0292824-A1 | Process for the nuclear chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |