Phthalimide

Phthalimide

SCHEMBL8853263

CC(=O)OO.O=C1NC(=O)c2ccccc21

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.62
CASP3 P42574 5/20 0.54
CASP2 P42575 2/20 0.54
CASP7 P55210 2/20 0.54
CASP6 P55212 2/20 0.54
CASP8 Q14790 2/20 0.54
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
POLB P06746 2/20 0.46
GPR55 Q9Y2T6 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
TGM2 P21980 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL1132405 0.87 GSK3B (0.75) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL4318901 0.85 GSK3B (0.71) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL11492689 0.83 GSK3B (0.68) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL10544624 0.83 GSK3B (0.68) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL10495296 0.81 GSK3B (0.54) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL5215747 0.80 GSK3B (0.71) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL27955087 0.80 GSK3B (0.79) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL15488735 0.80 GSK3B (0.79) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL23063638 0.79 GSK3B (0.88) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL11613247 0.79 GSK3B (0.62) GSK3BCASP3CASP2CASP7CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5575947-A BLEACH AUSIMONT S.R.L. (IT) 1996-11-19 US claimed
US-5520844-A Imide-aromatic peroxyacids as bleaching agents AUSIMONT S.P.A. (IT) 1996-05-28 US claimed
JP-9278747-A None JP disclosed
JP-2196771-A None JP disclosed
JP-2001473-A None JP disclosed
CN-103596742-B Improvements in moulding containers 雷克特本克斯尔菲尼施公司 2017-02-15 CN disclosed
US-5688434-A BLEACHING TEXTILES BY APPLYING BLEACHING AGENT AUSIMONT S.P.A. (IT) 1997-11-18 US disclosed
JP-H09278747-A REDUCTION OF WATER AND POLAR IMPURITY IN IMIDE-ALKANE PERCARBOXYLIC ACID AUSIMONT SPA 1997-10-28 JP disclosed
US-5575947-A BLEACH AUSIMONT S.R.L. (IT) 1996-11-19 US disclosed
US-5520844-A Imide-aromatic peroxyacids as bleaching agents AUSIMONT S.P.A. (IT) 1996-05-28 US disclosed
JP-H02196771-A NOVEL IMIDE-AROMATIC PEROXYACID AUSIMONT SRL 1990-08-03 JP disclosed
JP-H021473-A IMIDE AROMATIC PEROXY ACID AS BLEACHING AGENT AUSIMONT SPA 1990-01-05 JP disclosed