Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | AR | P10275 | 6/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.63 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | SHBG | P04278 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694580 | 1.00 | PGR (0.63) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL25863273 | 1.00 | PGR (0.63) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL6246812 | 1.00 | PGR (0.63) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL25863267 | 1.00 | PGR (0.63) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL25863270 | 1.00 | PGR (0.63) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL25863269 | 1.00 | PGR (0.63) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL11694584 | 0.99 | PGR (0.64) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL8853332 | 0.99 | PGR (0.64) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL8853386 | 0.97 | PGR (0.65) | PGRLMNAARSLC6A4CYP3A4 | |
| SCHEMBL30496613 | 0.93 | PGR (0.67) | PGRLMNAARSLC6A4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113406-A | GAS41 inhibitors and methods of use thereof | 密歇根大学董事会 | 2023-05-12 | — | — | CN | disclosed |
| US-5595759-A | Process for providing therapeutic composition | ALZA CORPORATION (US) | 1997-01-21 | — | — | US | disclosed |