SCHEMBL8853458

SCHEMBL8853458

CC(C)c1ccc(C(C)(C)OOC=CC(=O)OC(C)(C)OC(=O)O)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
POLB P06746 1/20 0.31
KIF11 P52732 1/20 0.30
TYR P14679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7692278 0.86 MAPK1 (0.43) CYP2D6HIF1AKDM4EMAPK1SMN1; SMN2
SCHEMBL9847930 0.77 CYP2D6 (0.35) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL8972266 0.77 CYP2D6 (0.33) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL9851460 0.75 LMNA (0.37) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL7685958 0.74
SCHEMBL9336311 0.73 NPC1 (0.37) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL9847991 0.72 EPHX1 (0.32) CYP2D6CYP2C9HIF1ASMN1; SMN2
SCHEMBL8763239 0.69
SCHEMBL11210123 0.68 MAPK1 (0.52) CYP2D6CYP2C9HIF1AMAPK1RAB9A
SCHEMBL7685055 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438098-A Blend of polyarylene sulfie;, polycarbonater and/or acrylonitrile-butadiene-styrene resin, and epoxy group containing defin graft polymer as compatibilizer NIPPON PETROCHEMICALS CO., LTD. (JP) 1995-08-01 US disclosed
US-5438108-A Melt-kneading a mixture of aromatic polycarbonate resin and vinylic copolymer containing active oxygen; optical distortion reduction MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-08-01 US disclosed
EP-0334296-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-06-07 EP disclosed
EP-0289933-B1 Graft polymerization precurser and method manufacturing the same NIPPON OILS & FATS CO LTD (JP) 1994-07-13 EP disclosed
US-5326817-A Blend of polyphenylene ether, polycarbonate or polyoxymethylene resins and multi-phase thermoplastic resins NIPPON PETROCHEMICALS CO. LTD. (JP) 1994-07-05 US disclosed
EP-0412572-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-13 EP disclosed
US-4987165-A MULTIPHASE COMPATIBILIZER FOR BLEND OF POLYSULFONE AND ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-01-22 US disclosed
US-4923956-A Containing free radical polymerizable organic peroxide NIPPON OIL AND FATS CO., LTD. (JP) 1990-05-08 US disclosed
US-4879347-A ETHYLENE POLYMER, VINYL MONOMER, RADICAL POLYMERIZABLE ORGANIC PEROXIDE, FREE RADICAL CATALYST, COPOLYMERIZATION NIPPON OIL AND FATS CO., LTD. (JP) 1989-11-07 US disclosed
US-4877841-A GRAFT POLYMER OF POLYETHYLENE, UNSATURATED MONOMER AND AN UNSATURATED PEROXYCARBONATE; SOLUBILIZERS FOR POLYMER BLENDS NIPPON OIL AND FATS CO., LTD. (JP) 1989-10-31 US disclosed
EP-0338544-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-10-25 EP disclosed
US-4839432-A USING A UNSATURATED PEROXY FREE RADICAL CATALYSTS NIPPON OIL AND FATS CO., LTD. (JP) 1989-06-13 US disclosed
EP-0289933-A2 Graft polymerization precurser and method manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
EP-0277608-A2 Graft polymerization preformer and method of manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-10 EP disclosed