Leucine

SCHEMBL8853541

CC(C)C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)Oc1ccc(C[C@H](N)C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.50

▸	NPY1R	P25929	9/20	0.50

▸	NPY5R	Q15761	8/20	0.48

▸	NPY2R	P49146	5/20	0.48

▸	SLC7A5	Q01650	1/20	0.42

▸	ITGB3	P05106	1/20	0.40

▸	ITGA2B	P08514	1/20	0.40

▸	ANPEP	P15144	1/20	0.39

▸	RNPEP	Q9H4A4	1/20	0.39

▸	DNPEP	Q9ULA0	1/20	0.39

▸	PTPN1	P18031	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1551972	0.93	SLC7A5 (0.47)	NPY4RNPY1RNPY5RNPY2RSLC7A5
SCHEMBL1231526	0.92	SLC7A5 (0.47)	NPY4RNPY1RNPY5RNPY2RSLC7A5
SCHEMBL10613823	0.91	NPY4R (0.47)	NPY4RNPY1RNPY5RNPY2RSLC7A5
Glutamic Acid SCHEMBL7759812	0.89	NPY4R (0.42)	NPY4RNPY1RNPY5RNPY2RSLC7A5
Glycine SCHEMBL5579222	0.89	ITGB3 (0.45)	NPY4RNPY1RNPY5RNPY2RSLC7A5
Arginine SCHEMBL8744510	0.87	NPY4R (0.44)	NPY4RNPY1RNPY5RNPY2RITGB3
Arginine SCHEMBL10610679	0.87	ITGB3 (0.51)	NPY4RNPY1RNPY5RNPY2RSLC7A5
Tyrosine SCHEMBL26115321	0.85	NPY4R (0.60)	NPY4RNPY1RNPY5RNPY2RSLC7A5
Arginine SCHEMBL27638364	0.85	ANPEP (0.52)	NPY4RNPY1RNPY5RNPY2RSLC7A5
Phenylalanine SCHEMBL11325686	0.84	NPY4R (0.46)	NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5610047-A	TREHALOSE	KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP)	1997-03-11	—	—	US	disclosed