Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297044 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTL3MBTL1LMNA | |
| SCHEMBL8854072 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTL3MBTL1LMNA | |
| SCHEMBL23863731 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTL3MBTL1LMNA | |
| SCHEMBL19175966 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPTL3MBTL1LMNA | |
| SCHEMBL25375145 | 0.78 | NPC1 (0.45) | ALDH1A1TSHRMAPTL3MBTL1LMNA | |
| SCHEMBL2493458 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL8265079 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL21055888 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL10336703 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL7762018 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424903-A1 | METHOD FOR PRODUCING SULFOXIDE DERIVATIVE | Kumiai Chemical Industry Co., Ltd. (JP) | 2019-01-09 | — | — | EP | disclosed |
| US-5659084-A | LEUKOTRIENE ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |