Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 2/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784566 | 0.79 | CA1 (0.56) | CA1CA2CA4CA6EDNRA | |
| SCHEMBL1291097 | 0.79 | CA1 (0.56) | CA1CA2CA4CA6EDNRA | |
| SCHEMBL6743749 | 0.77 | CA1 (0.58) | CA1CA2CA4CA6EDNRA | |
| SCHEMBL19576957 | 0.76 | RECQL (0.48) | CA1CA2CA4CA6EDNRA | |
| SCHEMBL13850926 | 0.76 | CA2 (0.47) | CA1CA2CA4CA6 | |
| SCHEMBL423104 | 0.76 | EDNRA (0.49) | CA1CA2EDNRAEDNRBMAPT | |
| SCHEMBL264098 | 0.72 | CA1 (0.52) | CA1CA2CA4CA6EDNRA | |
| SCHEMBL11697978 | 0.72 | GAA (0.54) | CA1CA2CA4CA6TDP1 | |
| SCHEMBL15915609 | 0.72 | EDNRA (0.54) | CA1CA2CA4CA6EDNRA | |
| SCHEMBL426958 | 0.72 | KAT6A (0.47) | EDNRAEDNRBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633400-A | CHEMICAL INTERMEDIATE FOR CARDIOVASCULAR DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |
| US-5618975-A | CHEMICAL INTERMEDIATES FOR CARDIOVASCULAR DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-08 | — | — | US | disclosed |