SCHEMBL8854437

SCHEMBL8854437

O=[PH](O)OCOS(=O)(=O)c1c(F)cccc1OC(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.31
HCRTR2 O43614 2/20 0.31
KCNN4 O15554 1/20 0.31
SCN9A Q15858 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854518 0.90 KCNN4 (0.32) HCRTR1HCRTR2KCNN4
SCHEMBL8854630 0.85 HCRTR1 (0.32) HCRTR1HCRTR2
SCHEMBL8734291 0.85 KCNN4 (0.32) HCRTR1HCRTR2KCNN4
SCHEMBL27451471 0.83
SCHEMBL8854450 0.82 PTGES2 (0.33)
SCHEMBL27467845 0.82
SCHEMBL8854750 0.81 SLC22A12 (0.37)
SCHEMBL8854552 0.80 KCNN4 (0.32) KCNN4
SCHEMBL8854543 0.80 KCNN4 (0.32) KCNN4
SCHEMBL8854692 0.79 FFAR4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173282-A Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners ROHM & HAAS (US) 1998-02-18 CN claimed
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed
CN-1133120-A Combination containing phosphine sulfonate ester herbicide and dichloro acetamide safety agent ROHM & HAAS (US) 1996-10-16 CN claimed