SCHEMBL8734291

SCHEMBL8734291

O=[PH](O)COS(=O)(=O)c1c(F)cccc1OC(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
EPHX2 P34913 1/20 0.31
KAT6A Q92794 1/20 0.31
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854437 0.85 HCRTR1 (0.31) KCNN4HCRTR1HCRTR2
SCHEMBL8732246 0.85 GABRA1 (0.33) EPHX2HCRTR1HCRTR2
SCHEMBL8854518 0.82 KCNN4 (0.32) KCNN4HCRTR1HCRTR2
SCHEMBL8730124 0.81 SLC22A12 (0.34) KAT6A
SCHEMBL8732648 0.80 SLC22A12 (0.39) RXRARXRBRXRG
SCHEMBL8734581 0.79 GAA (0.34) KCNN4RXRARXRBRXRGEPHX2
SCHEMBL8735547 0.78 FFAR4 (0.31)
SCHEMBL8735531 0.77 KEAP1 (0.35) KAT6A
SCHEMBL8854543 0.76 KCNN4 (0.32) KCNN4KAT6A
SCHEMBL8854552 0.76 KCNN4 (0.32) KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed