SCHEMBL8854516

SCHEMBL8854516

Cc1cccc(SC(F)(F)F)c1S(=O)(=O)OCO[PH2]=O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.31
FFAR4 Q5NUL3 2/20 0.31
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854478 0.86 FFAR4 (0.34) FFAR1FFAR4
SCHEMBL8854488 0.86
SCHEMBL8854589 0.85
SCHEMBL8854625 0.84 LMNA (0.33) LMNASMN1; SMN2
SCHEMBL8854512 0.82 FFAR4 (0.31) FFAR1FFAR4LMNAGAASMN1; SMN2
SCHEMBL8854644 0.82 FFAR1 (0.33) FFAR1FFAR4LMNAGAASMN1; SMN2
SCHEMBL8854459 0.82 GAA (0.32) GAA
SCHEMBL8854520 0.81 MEN1 (0.34)
SCHEMBL8854515 0.81 FFAR1 (0.34) FFAR1FFAR4
SCHEMBL8854532 0.79 FFAR4 (0.33) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed