Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340349 | 0.74 | TDP1 (0.44) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL723184 | 0.72 | ACLY (0.57) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL3712481 | 0.71 | TDP1 (0.46) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL16526145 | 0.71 | CYP2D6 (0.43) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL16405094 | 0.71 | CYP2D6 (0.43) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL11196284 | 0.69 | TDP1 (0.42) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL3282741 | 0.69 | SLC22A6 (0.43) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL29112587 | 0.67 | TDP1 (0.40) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL11200222 | 0.67 | TDP1 (0.40) | TDP1CPT2ACLYHSPD1BLM | |
| SCHEMBL22379 | 0.67 | FOLH1 (0.37) | TDP1CPT2ACLYHSPD1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625029-A | POLYLACTONE | EASTMAN CHEMICAL COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5552515-A | FROM SUBSTITUTED BETA-PROPIOLACTONES, ANIONIC CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5391708-A | High molecular weight biodegradable atactic polylactones | EASTMAN CHEMICAL COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| US-5281691-A | Carbon skeleton backbone or polymeric backbone bearing polycarboxylate functionality | EASTMAN KODAK COMPANY (US) | 1994-01-25 | — | — | US | disclosed |