Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855435 | 0.87 | TDP1 (0.44) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL11859665 | 0.86 | CYP3A4 (0.43) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL8855430 | 0.83 | CYP3A4 (0.43) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL8855540 | 0.80 | PLK1 (0.43) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL8855434 | 0.80 | MEN1 (0.45) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL11645452 | 0.80 | CYP2C9 (0.43) | CYP3A4ALDH1A1TDP1HPGDCYP2C19 | |
| SCHEMBL11644928 | 0.79 | CYP3A4 (0.37) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL11644925 | 0.79 | CYP3A4 (0.37) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL11643353 | 0.78 | CYP3A4 (0.34) | CYP3A4ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL11643349 | 0.78 | CYP3A4 (0.34) | CYP3A4ALDH1A1TDP1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670485-A | FEEDS FOR POULTRY WITH O-PHENYLENEDIAMINE OR BENZIMIDAZOLE WITH POLYETHER ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |