Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645452 | 0.89 | CYP2C9 (0.43) | MEN1KMT2AALDH1A1HPGDMITF | |
| SCHEMBL8855520 | 0.85 | MAPT (0.39) | MEN1KMT2AALDH1A1HPGDMITF | |
| SCHEMBL8855435 | 0.84 | TDP1 (0.44) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8855452 | 0.83 | MEN1 (0.45) | MEN1KMT2AALDH1A1HPGDMITF | |
| SCHEMBL11643098 | 0.81 | MAPT (0.37) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL11648114 | 0.81 | MEN1 (0.38) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11643162 | 0.80 | THRA (0.38) | MEN1KMT2AALDH1A1HPGDMITF | |
| SCHEMBL8855415 | 0.80 | CYP3A4 (0.42) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11643353 | 0.78 | CYP3A4 (0.34) | ALDH1A1HPGDMAPTLMNAHTT | |
| SCHEMBL11643349 | 0.78 | CYP3A4 (0.34) | ALDH1A1HPGDMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670485-A | FEEDS FOR POULTRY WITH O-PHENYLENEDIAMINE OR BENZIMIDAZOLE WITH POLYETHER ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-4122184-A | Benzimidazole insecticides | ELI LILLY AND COMPANY (US) | 1978-10-24 | — | — | US | disclosed |