Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | CCR10 | P46092 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9190400 | 0.89 | KMT2A (0.58) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL9085514 | 0.89 | KMT2A (0.58) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL8855564 | 0.88 | KMT2A (0.57) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL367445 | 0.88 | KMT2A (0.57) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL8895890 | 0.88 | KMT2A (0.57) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL8855559 | 0.88 | KMT2A (0.57) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL8895125 | 0.88 | KMT2A (0.57) | KMT2ALMNATHRBCYP2C19CA12 | |
| Hydrochloric Acid SCHEMBL8855504 | 0.86 | KMT2A (0.56) | KMT2ALMNATHRBCYP2C19CA12 | |
| Hydrochloric Acid SCHEMBL8855636 | 0.86 | KMT2A (0.56) | KMT2ALMNATHRBCYP2C19CA12 | |
| Bromide SCHEMBL5137846 | 0.86 | KMT2A (0.56) | KMT2ALMNATHRBCYP2C19CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652255-A | ADMINISTERING NITROIMIDAZOLE DERIVATIVE NITRIC OXIDE SYNTHASE INHIBITOR; ANTITUMOR AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-07-29 | — | — | US | claimed |
| US-5521203-A | INCREASES SENSITIVITY OF CELLS TO RADIATION AND CHEMOTHERAPY | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-05-28 | — | — | US | claimed |
| EP-0319329-B1 | Nitro-substituted aromatic or hetero-aromatic compounds for use in cancer treatment | BRITISH TECH GROUP (GB) | 1995-11-02 | — | — | EP | claimed |
| US-5098921-A | Antitumor agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-03-24 | — | — | US | claimed |
| EP-0319329-A2 | Nitro-substituted aromatic or hetero-aromatic compounds for use in cancer treatment | BTG INTERNATIONAL LIMITED (GB) | 1989-06-07 | — | — | EP | claimed |
| US-5652255-A | ADMINISTERING NITROIMIDAZOLE DERIVATIVE NITRIC OXIDE SYNTHASE INHIBITOR; ANTITUMOR AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| US-5521203-A | INCREASES SENSITIVITY OF CELLS TO RADIATION AND CHEMOTHERAPY | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0319329-B1 | Nitro-substituted aromatic or hetero-aromatic compounds for use in cancer treatment | BRITISH TECH GROUP (GB) | 1995-11-02 | — | — | EP | disclosed |
| US-5098921-A | Antitumor agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0319329-A2 | Nitro-substituted aromatic or hetero-aromatic compounds for use in cancer treatment | BTG INTERNATIONAL LIMITED (GB) | 1989-06-07 | — | — | EP | disclosed |