Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | GCG | P01275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376130 | 0.84 | TSHR (0.39) | ESR2ALDH1A1CYP3A4MEN1LMNA | |
| SCHEMBL29354035 | 0.81 | NPC1 (0.46) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL29903 | 0.81 | NPC1 (0.46) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL18093405 | 0.80 | ESR2 (0.34) | ESR2GCG | |
| SCHEMBL5510301 | 0.76 | NPC1 (0.41) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL12028081 | 0.75 | ESR2 (0.35) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL1499910 | 0.74 | NPC1 (0.45) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL6558920 | 0.74 | NPC1 (0.45) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL30393631 | 0.74 | NPC1 (0.45) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL10359709 | 0.74 | ESR1 (0.40) | ESR2ESR1ALDH1A1CYP3A4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684070-A | FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-04 | — | — | US | claimed |
| US-20160280863-A1 | MELT-STABILIZED ULTRA HIGH MOLECULAR WEIGHT ANTIOXIDANT | ZIMMER, INC. | 2016-09-29 | — | — | US | disclosed |
| US-5563242-A | LIGHT STABILITY | CIBA-GEIGY CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |