Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354035 | 0.80 | NPC1 (0.46) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL29903 | 0.80 | NPC1 (0.46) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL8680885 | 0.77 | KCNMA1 (0.48) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| Drometrizole SCHEMBL1011957 | 0.76 | NPC1 (0.62) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL5510301 | 0.75 | NPC1 (0.41) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL8855668 | 0.75 | ESR2 (0.37) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL15083635 | 0.74 | NPC1 (0.46) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL30393631 | 0.74 | NPC1 (0.45) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL6558920 | 0.74 | NPC1 (0.45) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL1499910 | 0.74 | NPC1 (0.45) | ESR2ESR1ALDH1A1CYP3A4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397510-A1 | High concentration pelletized additive concentrates for polymer | Ingenia Polymers Inc. (US) | 2011-12-21 | — | — | EP | disclosed |
| WO-2008033410-A1 | HIGH CONCENTRATION PELLETIZED ADDITIVE CONCENTRATES FOR POLYMER | INGENIA POLYMERS INC. (US) | 2008-03-20 | — | — | WO | disclosed |