Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654224 | 1.00 | MEN1 (0.51) | MEN1KMT2ALMNACYP1A2MAPT | |
| SCHEMBL12276489 | 0.83 | TRPA1 (0.55) | CYP1A2CYP2C9TRPA1 | |
| SCHEMBL3921874 | 0.83 | MAPT (0.67) | MEN1KMT2ALMNACYP1A2MAPT | |
| SCHEMBL4217444 | 0.83 | MAPT (0.53) | MEN1KMT2ALMNACYP1A2MAPT | |
| SCHEMBL16065669 | 0.83 | MAPT (0.46) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL10277228 | 0.83 | TRPA1 (0.55) | CYP1A2CYP2C9TRPA1 | |
| SCHEMBL10277230 | 0.83 | TRPA1 (0.55) | CYP1A2CYP2C9TRPA1 | |
| SCHEMBL28502066 | 0.83 | MAPT (0.46) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL9335450 | 0.83 | KDM4E (0.55) | MAPT | |
| SCHEMBL5606968 | 0.83 | KDM4E (0.55) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5675034-A | Process for preparing 2-(p-fluorophenyl)-2 methyl-propionic acid and 3-(p-fluorophenyl)-2-methylpropionic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | disclosed |