Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222848 | 0.98 | NAAA (0.58) | NAAACA1CCR2ACE2ZDHHC7 | |
| Ammonia Solution, Strong SCHEMBL27918763 | 0.97 | NAAA (0.56) | NAAACA1CCR2ACE2ZDHHC7 | |
| SCHEMBL7218260 | 0.97 | NAAA (0.55) | NAAACA1CCR2ACE2ZDHHC7 | |
| SCHEMBL29233727 | 0.93 | NAAA (0.47) | NAAACA1CCR2ACE2ZDHHC7 | |
| SCHEMBL4743690 | 0.92 | NAAA (0.53) | NAAACA1CCR2EPHX1CYP19A1 | |
| SCHEMBL27200276 | 0.92 | CA1 (0.48) | NAAACA1CCR2ACE2ZDHHC7 | |
| SCHEMBL10880143 | 0.86 | NAAA (0.46) | NAAAEPHX1CYP19A1CHRM2CHRM1 | |
| SCHEMBL18098094 | 0.85 | CYP19A1 (0.40) | NAAACCR2EPHX1CYP19A1CHRM2 | |
| SCHEMBL4778909 | 0.85 | CA1 (0.46) | NAAACA1CCR2ACE2ZDHHC7 | |
| SCHEMBL4743509 | 0.85 | NAAA (0.47) | NAAAEPHX1CYP19A1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102281919-A | Inhibitors of diacylglycerol acyltransferase | — | 2011-12-14 | — | — | CN | disclosed |
| US-5656634-A | N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) | PFIZER INC. (US) | 1997-08-12 | — | — | US | disclosed |