⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316942 | 0.97 | DNM1 (0.40) | — | |
| SCHEMBL10628467 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL2015577 | 0.80 | — | — | |
| SCHEMBL131014 | 0.77 | — | — | |
| SCHEMBL8676090 | 0.76 | — | — | |
| SCHEMBL19774576 | 0.75 | TSHR (0.52) | — | |
| SCHEMBL132137 | 0.75 | TSHR (0.52) | — | |
| SCHEMBL131017 | 0.75 | TSHR (0.52) | — | |
| SCHEMBL129565 | 0.75 | — | — | |
| SCHEMBL3168896 | 0.75 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640094-A | Compounds as PRMT1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-116265453-A | Compounds as AR inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-111662227-B | O-aminopyridine alkyne compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-07-05 | — | — | CN | claimed |
| WO-2021068953-A1 | SUBSTITUTED TRICYCLIC COMPOUND AS PRMT5 INHIBITOR AND USE THEREOF | 南京圣和药业股份有限公司 | 2021-04-15 | — | — | WO | claimed |
| WO-2020200158-A1 | N-HETEROAROMATIC AMIDE DERIVATIVES FOR TREATMENT OF CANCER | 深圳福沃药业有限公司 | 2020-10-08 | — | — | WO | claimed |
| CN-111662227-A | O-aminopyridine alkyne compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-09-15 | — | — | CN | claimed |
| EP-2362727-B1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | CEMPRA PHARMACEUTICALS INC (US) | 2018-04-11 | — | — | EP | claimed |
| CN-102014617-B | Emulsifiable concentrate | BASF SE (DE) | 2014-10-01 | — | — | CN | claimed |
| CN-102811616-A | Parenteral formulations of macrolide antibiotics | CEMPRA PHARMACEUTICALS INC | 2012-12-05 | — | — | CN | claimed |
| CN-102724874-A | Methods of treating malaria, tuberculosis, and MAC disease | CEMPRA PHARMACEUTICALS INC | 2012-10-10 | — | — | CN | claimed |
| CN-102271505-A | Synthesis of (2-amino)-tetrahydrocarbazole-propanoic acid | — | 2011-12-07 | — | — | CN | claimed |
| CN-101917850-A | Macrolide antibacterial agent and its preparation method | CEMPRA PHARMACEUTICALS INC | 2010-12-15 | — | — | CN | claimed |
| CN-100481574-C | Organic electro luminous device | LG DISPLAY CO LTD (KR) | 2009-04-22 | — | — | CN | claimed |
| CN-101406473-A | Use of dihydropyrimidine compound and pharmaceutical composition containing the same | SHANGHAI INST ORGANIC CHEM (CN) | 2009-04-15 | — | — | CN | claimed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | claimed |
| CN-101031299-A | Thienopyridinone compounds and methods of treatment | EPIX DELAWARE INC (US) | 2007-09-05 | — | — | CN | claimed |
| WO-2007081091-A1 | RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-07-19 | — | — | WO | claimed |
| CN-1874677-A | Nanoparticulate active substance formulations | BASF AG (DE) | 2006-12-06 | — | — | CN | claimed |
| CN-1535089-A | Organic electro luminous device | LG������ʽ���� | 2004-10-06 | — | — | CN | claimed |
| CN-1305480-A | Pyrrolo [2, 3-d ] pyrimidine compounds | PFIZER PROD INC (US) | 2001-07-25 | — | — | CN | claimed |