Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175097 | 0.83 | FABP3 (0.49) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL704708 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1GLAGAACLCN2 | |
| SCHEMBL3787249 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1GAALMNAATM | |
| SCHEMBL8061202 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL13450268 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL11500348 | 0.79 | PDK1 (0.60) | KDM4EALDH1A1GAALMNAFABP3 | |
| SCHEMBL28282536 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL12316320 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL3478288 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL3788998 | 0.75 | MAPT (0.44) | KDM4EALDH1A1GLAGAAFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698556-A | TREATING CANCER | CHAN CARCY L (US) | 1997-12-16 | — | — | US | disclosed |