Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141149 | 1.00 | BACE1 (0.52) | BACE1TSHRSMN1; SMN2EDNRAEDNRB | |
| SCHEMBL3201276 | 1.00 | BACE1 (0.52) | BACE1TSHRSMN1; SMN2EDNRAEDNRB | |
| SCHEMBL8573735 | 1.00 | BACE1 (0.52) | BACE1TSHRSMN1; SMN2EDNRAEDNRB | |
| SCHEMBL3201279 | 1.00 | BACE1 (0.52) | BACE1TSHRSMN1; SMN2EDNRAEDNRB | |
| SCHEMBL8503544 | 1.00 | BACE1 (0.52) | BACE1TSHRSMN1; SMN2EDNRAEDNRB | |
| SCHEMBL15446338 | 0.88 | BACE1 (0.46) | BACE1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL15446214 | 0.87 | TSHR (0.53) | BACE1TSHRSMN1; SMN2EDNRAEDNRB | |
| SCHEMBL7906596 | 0.86 | TSHR (0.54) | BACE1TSHRMAPTALDH1A1CA1 | |
| SCHEMBL7902731 | 0.86 | TSHR (0.54) | BACE1TSHRMAPTALDH1A1CA1 | |
| SCHEMBL7906590 | 0.86 | TSHR (0.54) | BACE1TSHRMAPTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2693248-B2 | — | — | 1997-12-24 | — | — | JP | claimed |
| EP-0440723-A4 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | — | 1992-05-20 | — | — | EP | claimed |
| EP-0440723-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS. | SEPRACOR INC (US) | 1991-08-14 | — | — | EP | claimed |
| WO-1990004643-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | SEPRACOR, INC. (US) | 1990-05-03 | — | — | WO | claimed |
| US-7220870-B2 | Hydrolytic kinetic resolution of cyclic substrates | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-05-22 | — | — | US | disclosed |
| US-7220870-B2 | Hydrolytic kinetic resolution of cyclic substrates | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-05-22 | — | — | US | disclosed |