Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856992 | 0.76 | FOLH1 (0.55) | FOLH1MCL1TP53CNR2EDNRB | |
| SCHEMBL8857072 | 0.76 | TP53 (0.64) | FOLH1MCL1TP53CNR2MAPT | |
| SCHEMBL8857042 | 0.75 | FOLH1 (0.70) | FOLH1MCL1PLA2G2ATP53POLB | |
| SCHEMBL5669208 | 0.72 | CNR2 (0.54) | FOLH1PLA2G2ATP53LMNACNR2 | |
| SCHEMBL8857055 | 0.72 | FOLH1 (0.62) | FOLH1MCL1TP53CNR2 | |
| SCHEMBL6219757 | 0.72 | CNR2 (0.56) | MEN1KMT2ALMNACNR2MAPT | |
| SCHEMBL8857009 | 0.69 | MCL1 (0.58) | FOLH1MCL1TP53EDNRB | |
| SCHEMBL8857037 | 0.68 | FOLH1 (0.54) | FOLH1MCL1PLA2G2ATP53CNR2 | |
| SCHEMBL8973826 | 0.67 | TDP1 (0.57) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL9263671 | 0.67 | MCL1 (0.61) | MCL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684032-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC, ANTIASTHMATIC AGENTS AND RESPIRATORY DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |