Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 10/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | EDNRB | P24530 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857072 | 0.91 | TP53 (0.64) | FOLH1TP53MCL1EDNRBEDNRA | |
| SCHEMBL8857042 | 0.86 | FOLH1 (0.70) | FOLH1TP53MCL1 | |
| SCHEMBL8857055 | 0.83 | FOLH1 (0.62) | FOLH1TP53MCL1CNR2 | |
| SCHEMBL8857009 | 0.81 | MCL1 (0.58) | FOLH1TP53MCL1EDNRBEDNRA | |
| SCHEMBL8857037 | 0.81 | FOLH1 (0.54) | FOLH1TP53MCL1CNR2CCR2 | |
| SCHEMBL5669208 | 0.79 | CNR2 (0.54) | FOLH1TP53CNR2 | |
| SCHEMBL8856965 | 0.76 | FOLH1 (0.48) | FOLH1TP53MCL1EDNRBCNR2 | |
| SCHEMBL9268492 | 0.75 | PLA2G2A (0.64) | — | |
| SCHEMBL15622969 | 0.74 | MCL1 (0.76) | FOLH1MCL1 | |
| SCHEMBL9263671 | 0.73 | MCL1 (0.61) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684032-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC, ANTIASTHMATIC AGENTS AND RESPIRATORY DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |