Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8857142

CCCCCCCCc1ccc(COC(C)=O)c(CCCCCCCC)c1CCCCCCCC.N

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.45
TYR P14679 2/20 0.45
TSHR P16473 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PPARA Q07869 3/20 0.45
PPARG P37231 2/20 0.45
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
ALDH1A1 P00352 1/20 0.40
EP300 Q09472 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL8857023 0.97 ALOX5 (0.45) ALOX5TYRTSHRMEN1KMT2A
Ammonia Solution, Strong SCHEMBL11743323 0.88 TYR (0.40) ALOX5TYRTSHRMEN1KMT2A
SCHEMBL17027813 0.83 PPARA (0.52) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL28660487 0.80 ALOX5 (0.44) ALOX5TYRTSHRMEN1KMT2A
SCHEMBL30876168 0.79 TYR (0.57) ALOX5TYRTSHRMEN1KMT2A
SCHEMBL10608218 0.79 TYR (0.57) ALOX5TYRTSHRMEN1KMT2A
SCHEMBL11331495 0.79 TYR (0.57) ALOX5TYRTSHRMEN1KMT2A
SCHEMBL11337178 0.79 TYR (0.57) ALOX5TYRTSHRMEN1KMT2A
SCHEMBL1822032 0.79 TYR (0.57) ALOX5TYRTSHRMEN1KMT2A
SCHEMBL7571565 0.79 TYR (0.57) ALOX5TYRTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670868-B1 FLUORORUBBER COATING COMPOSITION MINNESOTA MINING & MFG (US) 1997-01-22 EP disclosed
EP-0670868-A1 FLUORORUBBER COATING COMPOSITION. MINNESOTA MINING & MFG (US) 1995-09-13 EP disclosed
WO-1994012580-A1 FLUORORUBBER COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-09 WO disclosed