Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857747 | 0.98 | RARB (0.60) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL8857746 | 0.98 | RARB (0.60) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL8375670 | 0.97 | RARB (0.59) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL17586078 | 0.97 | RARB (0.55) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL8990651 | 0.96 | RARB (0.61) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL17586077 | 0.93 | RARB (0.50) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL8990757 | 0.93 | RARB (0.53) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL8375674 | 0.91 | RARB (0.50) | RARBKCNH2RARARARGCTRC | |
| SCHEMBL9398982 | 0.91 | RARB (0.68) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL3157443 | 0.89 | RARB (0.51) | RARBKCNH2RARARARGCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180223187-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-5637257-A | LIQUID CRYSTAL DISPLAYING | MERCK PATENT GESELLSCHAFT MLT BESCHRANKTER HAFTUNG (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5482653-A | FOR LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-01-09 | — | — | US | disclosed |
| EP-0428666-A1 | FLUORO-CHLORO-BENZENE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990015113-A1 | FLUORO-CHLORO-BENZENE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |