Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375670 | 0.96 | RARB (0.59) | RARBCTRCKCNH2RARARARG | |
| SCHEMBL8990651 | 0.94 | RARB (0.61) | RARBCTRCKCNH2RARARARG | |
| SCHEMBL17586077 | 0.94 | RARB (0.50) | RARBCTRCKCNH2RARARARG | |
| SCHEMBL8857743 | 0.93 | RARB (0.58) | RARBCTRCKCNH2RARARARG | |
| SCHEMBL9662908 | 0.92 | RARB (0.59) | RARBRARARARGMPLCHKA | |
| SCHEMBL8857747 | 0.91 | RARB (0.60) | RARBCTRCKCNH2RARARARG | |
| SCHEMBL8857746 | 0.91 | RARB (0.60) | RARBCTRCKCNH2RARARARG | |
| SCHEMBL8507964 | 0.91 | RARB (0.46) | RARBCTRCMCHR1MAOBGRM2 | |
| SCHEMBL10975470 | 0.91 | RARB (0.61) | RARBRARARARGMPLCHKA | |
| SCHEMBL17586078 | 0.90 | RARB (0.55) | RARBCTRCKCNH2RARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |