Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154708 | 1.00 | PROKR1 (0.37) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL10988724 | 0.94 | SIGMAR1 (0.38) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL8447263 | 0.91 | MAOB (0.44) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL8447260 | 0.91 | MAOB (0.44) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL8160602 | 0.91 | SIGMAR1 (0.40) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL8160596 | 0.91 | PROKR1 (0.37) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL6452577 | 0.90 | PROKR1 (0.39) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL6452568 | 0.90 | PROKR1 (0.39) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL8154901 | 0.90 | SIGMAR1 (0.41) | PROKR1FPR2SIGMAR1MAOBMAOA | |
| SCHEMBL8971558 | 0.90 | CYP11B1 (0.36) | PROKR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637257-A | LIQUID CRYSTAL DISPLAYING | MERCK PATENT GESELLSCHAFT MLT BESCHRANKTER HAFTUNG (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5482653-A | FOR LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-01-09 | — | — | US | disclosed |
| EP-0426815-B1 | FLUORINATED BIPHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 1994-12-14 | — | — | EP | disclosed |
| WO-1990015115-A1 | FLUORINATED BIPHENYL DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |
| WO-1990015113-A1 | FLUORO-CHLORO-BENZENE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |