Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8858449

CC(C(=O)O)C(C)(C)CC(=O)O.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.44
CHRM1 P11229 1/20 0.44
TBXA2R P21731 1/20 0.44
ADRA1A P35348 1/20 0.44
CYP2C19 P33261 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 2/20 0.40
CYP1A2 P05177 1/20 0.39
CPT2 P23786 2/20 0.38
KDM4E B2RXH2 1/20 0.38
FFAR1 O14842 1/20 0.38
ACLY P53396 1/20 0.35
TP53 P04637 1/20 0.33
BHMT Q93088 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8858444 1.00 HMGCR (0.44) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL7960610 0.98 HMGCR (0.46) HMGCRCHRM1TBXA2RADRA1ACYP2C19
Tetramethylammonium Ion SCHEMBL8858493 0.91 HMGCR (0.41) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL27680767 0.79 TSHR (0.33) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL1572172 0.77 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL28632313 0.76 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL1572639 0.75 CYP1A2 (0.37) CHRM1ADRA1ATDP1CYP1A2TP53
SCHEMBL15040910 0.75 CYP1A2 (0.37) CHRM1ADRA1ATDP1CYP1A2TP53
SCHEMBL20702101 0.75 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL4585507 0.75 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9082579-A None JP disclosed
JP-H0982579-A ELECTROLYTE FOR ELECTROLYTIC CAPACITOR HITACHI AIC INC 1997-03-28 JP disclosed