Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572639 | 1.00 | CYP1A2 (0.37) | CYP1A2TP53CHRM1AKR1A1CHRM3 | |
| SCHEMBL11566634 | 0.81 | TSHR (0.30) | TDP1 | |
| SCHEMBL16331317 | 0.80 | ADRA1A (0.37) | CYP1A2TP53CHRM1AKR1A1CHRM3 | |
| SCHEMBL19545997 | 0.79 | ALDH1A1 (0.32) | TDP1ALDH1A1 | |
| SCHEMBL27680767 | 0.78 | TSHR (0.33) | CYP1A2TP53CHRM1AKR1A1CHRM3 | |
| SCHEMBL23461210 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL19832370 | 0.77 | CA1 (0.37) | CA2 | |
| SCHEMBL7960610 | 0.77 | HMGCR (0.46) | CYP1A2TP53CHRM1ADRA1ATDP1 | |
| SCHEMBL2332912 | 0.77 | CYP1A2 (0.36) | CYP1A2TP53GABRR1RNPEPALDH1A1 | |
| SCHEMBL29956302 | 0.77 | ALDH1A1 (0.35) | CYP1A2TP53CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604697-A1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | Tokyo University of Agriculture and Technology TLO (JP) | 2013-06-19 | — | — | EP | disclosed |