Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858741 | 0.93 | SCN4A (0.41) | SCN4AEPHX2EPHX1STSPOLB | |
| SCHEMBL8858707 | 0.84 | ADORA1 (0.39) | SCN4ASTSGRAMD1APTPN2PTPN1 | |
| SCHEMBL31164700 | 0.79 | GRAMD1A (0.50) | SCN4AGRAMD1ASCN5ASCN3A | |
| SCHEMBL8858785 | 0.78 | HDAC4 (0.49) | POLBDRD2DRD3GRAMD1APTPN2 | |
| SCHEMBL8858803 | 0.77 | POLB (0.43) | POLBDRD2DRD3 | |
| SCHEMBL8858588 | 0.77 | POLB (0.47) | POLBDRD2DRD3ALDH1A1 | |
| SCHEMBL8858628 | 0.76 | POLB (0.40) | POLBDRD2DRD3ALDH1A1 | |
| SCHEMBL8858634 | 0.75 | USP30 (0.49) | POLBDRD2DRD3GRAMD1AALDH1A1 | |
| SCHEMBL3879929 | 0.75 | HRH3 (0.41) | SCN4AEPHX1 | |
| SCHEMBL8858848 | 0.73 | POLB (0.43) | POLBDRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607944-A | ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0639575-A1 | Bicyclic heterocycles, medicaments comprising these compounds and processes for their production | Dr. Karl Thomae GmbH (DE) | 1995-02-22 | — | — | EP | disclosed |