Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323173 | 0.90 | RNASE1 (0.51) | RNASE1TYMSTK1 | |
| SCHEMBL25399868 | 0.89 | RNASE1 (0.63) | RNASE1TK1 | |
| SCHEMBL25764517 | 0.89 | RNASE1 (0.63) | RNASE1TK1 | |
| SCHEMBL25400848 | 0.89 | RNASE1 (0.63) | RNASE1TK1 | |
| SCHEMBL4808054 | 0.89 | RNASE1 (0.63) | RNASE1TK1 | |
| SCHEMBL4808051 | 0.89 | RNASE1 (0.63) | RNASE1TK1 | |
| SCHEMBL6830424 | 0.87 | RNASE1 (0.49) | RNASE1TYMSTK1 | |
| SCHEMBL30396378 | 0.87 | RNASE1 (0.54) | RNASE1TYMSTK1 | |
| SCHEMBL25395896 | 0.86 | TOP2A (0.56) | RNASE1TK1 | |
| SCHEMBL25401183 | 0.86 | TOP2A (0.56) | RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625050-A | Modified oligonucleotides and intermediates useful in nucleic acid therapeutics | AMGEN INC. (US) | 1997-04-29 | — | — | US | disclosed |