Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51367 | 0.86 | CES1 (0.64) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL6363616 | 0.84 | CES1 (0.61) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL9111034 | 0.84 | CES1 (0.61) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL3966085 | 0.82 | AKR1B1 (0.65) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL27293995 | 0.81 | CES1 (0.64) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL1493 | 0.81 | CES1 (0.64) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL77563 | 0.81 | CES1 (0.70) | CES1CES2AKR1B1MEN1KMT2A | |
| Hydrogen Sulfide SCHEMBL27809609 | 0.79 | CES1 (0.61) | CES1CES2AKR1B1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3047868 | 0.79 | CES1 (0.61) | CES1CES2AKR1B1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27690655 | 0.79 | CES1 (0.67) | CES1CES2AKR1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997011704-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1997-04-03 | — | — | WO | disclosed |