SCHEMBL51367

SCHEMBL51367

O=C(CC(=O)Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.64
CES2 O00748 1/20 0.64
AKR1B1 P15121 1/20 0.64
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
EPHX2 P34913 1/20 0.56
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 2/20 0.50
MAPK1 P28482 1/20 0.50
CTBP2 P56545 1/20 0.50
CNR2 P34972 1/20 0.50
GAA P10253 2/20 0.48
HPGD P15428 1/20 0.48
PAM P19021 2/20 0.48
FFAR1 O14842 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6363616 0.97 CES1 (0.61) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL9111034 0.97 CES1 (0.61) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL3966085 0.90 AKR1B1 (0.65) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL77563 0.89 CES1 (0.70) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL7503862 0.89 CES2 (0.52) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL9693670 0.86 CES1 (0.67) CES1CES2AKR1B1MEN1KMT2A
Hydrochloric Acid SCHEMBL27690655 0.86 CES1 (0.67) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL5217028 0.86 CES1 (0.54) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL9079361 0.86 CES1 (0.54) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL8860009 0.86 CES1 (0.54) CES1CES2AKR1B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2197829-B1 ARYLAMINE SYNTHESIS METHOD CENTRE NAT RECH SCIENT (FR) 2016-05-04 EP claimed
US-8399680-B2 Arylamine synthesis method CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-03-19 US claimed
US-20100298571-A1 ARYLAMINE SYNTHESIS METHOD CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-25 US claimed
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 EP claimed
EP-1562964-B1 PALLADIUM AND PLATINUM COMPLEXES MERCK PATENT GMBH (DE) 2006-07-19 EP claimed
US-20040138455-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-15 US claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
US-4116869-A POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1978-09-26 US claimed
US-4095017-A VINYL MONOMER POLYMERIZATION OR COPOLYMERIZATION CATALYZED BY ORGANOALUMINUM-ORGANOPHOSPHINE-METAL SALT OF A BETA-DIKETONE CATALYST SYSTEM PHILLIPS PETROLEUM COMPANY (US) 1978-06-13 US claimed
US-4020018-A Alkene oxide or acrylate polymerization or copolymerization catalyzed by organoaluminum-organophosphine-metal salt of a beta-diketone PHILLIPS PETROLEUM COMPANY (US) 1977-04-26 US claimed
US-3989741-A ALKYLATION, REDUCTION, TRANSESTERIFICATION, ESTER-SUBSTITUTED PHENOLS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-11-02 US claimed
US-12635401-B2 Metal complexes UDC Ireland (IE) 2026-05-19 US disclosed
US-20260070936-A1 METAL COMPLEXES UDC IRELAND LTD (IE) 2026-03-12 US disclosed
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 EP disclosed
US-12250871-B2 Metal complexes UDC IRELAND LIMITED (IE) 2025-03-11 US disclosed
US-4036605-A CATALYZING OXIDATION OF HYDROCARBONS WITH A B-KETOENOLATE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-07-19 US disclosed
US-4029713-A ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-06-14 US disclosed
US-4020018-A Alkene oxide or acrylate polymerization or copolymerization catalyzed by organoaluminum-organophosphine-metal salt of a beta-diketone PHILLIPS PETROLEUM COMPANY (US) 1977-04-26 US disclosed
US-3989741-A ALKYLATION, REDUCTION, TRANSESTERIFICATION, ESTER-SUBSTITUTED PHENOLS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-11-02 US disclosed
US-3935316-A Method of use and formulations THE UPJOHN COMPANY (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070936-A1 METAL COMPLEXES SCO2, CBR1, CORO1C CES1 2189/4885CES2 1956/4885AKR1B1 934/4885
US-12635401-B2 Metal complexes SCO2, SOD1, NR4A1 CES1 4058/4885CES2 2075/4885AKR1B1 2502/4885
US-20040138455-A1 Rhodium and iridium complexes RPIA, MPI, INPP5B CES1 4725/4885CES2 3866/4885AKR1B1 3843/4885
US-12250871-B2 Metal complexes AP1M1, SOD1, AP3M1 CES1 4808/4885CES2 3040/4885AKR1B1 4654/4885
US-20100298571-A1 ARYLAMINE SYNTHESIS METHOD NAT1, ASNS, AOC2 CES1 1684/4885CES2 369/4885AKR1B1 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.