Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 10/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344813 | 0.87 | MAPK9 (0.66) | MAPK9PTGS2MALT1PTGS1CHRNA7 | |
| SCHEMBL8639277 | 0.72 | PTGS2 (0.44) | MAPK9PTGS2PTGS1CACNA1GCACNA1H | |
| SCHEMBL8015867 | 0.71 | PTGS2 (0.65) | PTGS2MALT1PTGS1 | |
| SCHEMBL6345557 | 0.71 | MAPK9 (0.71) | MAPK9PTGS2MALT1PTGS1CHRNA7 | |
| SCHEMBL8421778 | 0.71 | PTGS2 (0.56) | MAPK9MEN1KMT2AMAPTPTGS2 | |
| SCHEMBL8423901 | 0.71 | PTGS2 (0.51) | MAPK9MEN1KMT2APTGS2PTGS1 | |
| SCHEMBL8420097 | 0.71 | PTGS2 (0.51) | MAPK9MEN1KMT2APTGS2PTGS1 | |
| SCHEMBL8644150 | 0.70 | PTGS2 (0.51) | PTGS2MALT1PTGS1 | |
| SCHEMBL8641149 | 0.70 | MAPK9 (0.46) | MAPK9MEN1KMT2APTGS2MALT1 | |
| SCHEMBL8638131 | 0.70 | PTGS2 (0.43) | MAPK9PTGS2PTGS1CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997011704-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1997-04-03 | — | — | WO | claimed |