Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.69 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.69 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.68 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.68 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.68 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.67 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.65 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.65 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.65 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.64 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.64 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.64 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861594 | 0.93 | DNPH1 (0.70) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| SCHEMBL15721190 | 0.86 | P2RY1 (0.75) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| SCHEMBL1063333 | 0.86 | P2RY1 (0.75) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| Adenosine Triphosphate SCHEMBL28252560 | 0.86 | P2RY1 (0.91) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| SCHEMBL5848304 | 0.85 | ENPP1 (0.73) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| SCHEMBL4997435 | 0.84 | P2RY1 (0.94) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| Adenosine Triphosphate SCHEMBL8980 | 0.84 | P2RY1 (0.94) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| Adenosine Triphosphate SCHEMBL18089781 | 0.84 | P2RY1 (0.94) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| Adenosine Triphosphate SCHEMBL20550531 | 0.84 | P2RY1 (0.94) | P2RX3P2RX2P2RY1P2RY2P2RX4 | |
| SCHEMBL376009 | 0.84 | P2RY1 (0.94) | P2RX3P2RX2P2RY1P2RY2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620676-A | ADENOSINE TRIPHOSPHATE DERIVATIVES; TREATMENT OF SEPTIC SHOCK OR BRAIN SEIZURES, LEARNING ENHANCEMENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-04-15 | — | — | US | disclosed |